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The influence of brain death on donor liver and the potential mechanisms of protective intervention

null

《医学前沿(英文)》 2011年 第5卷 第1期   页码 8-14 doi: 10.1007/s11684-011-0109-y

摘要:

Brain-dead donors have become one of the main sources of organs for transplantation in Western countries. The quality of donor organs is closely related to the outcome of the transplantation. Experimental studies have confirmed the inferior graft survival of livers from brain-dead donors compared with those from living donors. Studies conducted in the past 10 years have shown that brain death is associated with effects on the decreased donor organ quality. However, whether the decrease in the viability of donor organs is caused by brain death or by the events before and after brain death remains uncertain. The purpose of this review is to introduce the advances and controversies regarding the influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective interventions for donor livers.

关键词: brain death     donor liver    

Theoretical insights into influence of additives on sulfamethoxazole crystal growth kinetics and mechanisms

《化学科学与工程前沿(英文)》 2023年 第17卷 第10期   页码 1503-1515 doi: 10.1007/s11705-022-2294-4

摘要: In this work, the influence of the initial chemical potential gradient, stirring speed, and polymer type on sulfamethoxazole (SMX) crystal growth kinetics was systematically investigated through density functional theory (DFT) calculations, experimental measurements and the two-step chemical potential gradient model. To investigate the influence of different conditions on the thermodynamic driving force of SMX crystal growth, SMX solubilities in different polymer solutions were studied. Four model polymers effectively improved SMX solubility. It was further found that polyvinylpyrrolidone (PVP) and hydroxypropyl methyl cellulose (HPMC) played a crucial role in inhibiting SMX crystal growth. However, polyethylene glycol (PEG) promoted SMX crystal growth. The effect of the polymer on the crystal growth mechanisms of SMX was further analyzed by the two-step chemical potential gradient model. In the system containing PEG 6000, crystal growth is dominated by the surface reaction. However, in the system containing PEG 20000, crystal growth is dominated by both the surface reaction and diffusion. In addition, DFT calculations results showed that HPMC and PVP could form strong and stable binding energies with SMX, indicating that PVP and HPMC had the potential ability to inhibit SMX crystal growth.

关键词: insoluble drugs     polymer     inhibition crystallization     crystal growth kinetics     DFT calculations    

Influence of extracellular polymeric substances from activated sludge on the aggregation kinetics of

《环境科学与工程前沿(英文)》 2022年 第16卷 第2期 doi: 10.1007/s11783-021-1450-2

摘要:

• The NPs aggregation in the electrolyte solution is consistent with the DLVO theory.

关键词: Silver nanoparticles     Silver sulfide nanoparticles     Extracellular polymeric substances     Aggregation kinetics     Influence mechanisms    

Catalytic activity of noble metal nanoparticles toward hydrodechlorination: influence of catalyst electronic

Man ZHANG,Feng HE,Dongye ZHAO

《环境科学与工程前沿(英文)》 2015年 第9卷 第5期   页码 888-896 doi: 10.1007/s11783-015-0774-1

摘要: In this study, stabilized Pd, Pt and Au nanoparticles were successfully prepared in aqueous phase using sodium carboxymethyl cellulose (CMC) as a capping agent. These metal nanoparticles were then tested for catalytic hydrodechlorination toward two classes of organochlorinated compounds (vinyl polychlorides including trichloroethylene (TCE), tetrachloroethylene (PCE), and alkyl polychlorides including 1,1,1-trichloroethane (1,1,1-TCA), and 1,1,1,2-tetrachloroethane (1,1,1,2-TeCA)) to determine the rate-limiting steps and to explore the reaction mechanisms. The surface area normalized reaction rate constant, , showed a systematic dependence on the electronic structure (the density of states at the Fermi level) of the metals, suggesting that adsorption of organochlorinated reactants on the metal catalyst surfaces is the rate-limiting step for catalytic hydrodechlorination. Hydrodechlorination rates of 1,1,1-TCA and 1,1,1,2-TeCA agreed with the bond strength of the first (weakest) dissociated C-Cl bond, suggesting that C-Cl bond cleavage, which is the first step for dissociative adsorption of the alkyl polychlorides, controlled the catalytic hydrodechlorination rate. However, hydrodechlorination rates of TCE and PCE correlated with the adsorption energies of their molecular (non-dissociative) adsorption on the noble metals rather than with the first C-Cl bond strength, suggesting that molecular adsorption governs the reaction rate for hydrodechlorination of the vinyl polychlorides.

关键词: catalytic hydrodechlorination     electronic structure     metal nanoparticles     reaction mechanisms    

FOOD SYSTEMS TRANSFORMATION: CONCEPTS, MECHANISMS AND PRACTICES

《农业科学与工程前沿(英文)》 2023年 第10卷 第1期   页码 1-3 doi: 10.15302/J-FASE-2023491

摘要: FOOD SYSTEMS TRANSFORMATION: CONCEPTS, MECHANISMS AND PRACTICES

关键词: TRANSFORMATION     SYSTEMS     FOOD     CONCEPTS     MECHANISMS    

Gripping mechanisms in current wood harvesting machines

D. GOUBET, J. C. FAUROUX, G. GOGU

《机械工程前沿(英文)》 2013年 第8卷 第1期   页码 42-61 doi: 10.1007/s11465-013-0358-3

摘要:

This paper focuses on the structural synthesis of gripping mechanisms used in the mechanization of the harvesting process. The importance of the gripping function in current devices like harvesting heads is underlined. This function is performed with several typical mechanisms which are listed and described in this article. This study distinguishes two kinds of planar gripping mechanisms mainly used in opening and closing the rollers: five concentric and two lateral ones. Both kinds have advantages and drawbacks. So a third kind of hybrid mechanism has been designed in order to orientate the axis of the rollers during gripping motion in order to combine concentric and lateral gripping advantages. Two planar and one spatial existing mechanisms are described. The last part of this paper presents a structural synthesis of such a spatial parallel mechanism by using the structural parameters and the general formulae established by the third author. Nine kinematic diagrams of spatial parallel mechanisms are provided.

关键词: structural synthesis     parallel mechanisms     gripping mechanisms     wood harvesting     harvesting head    

Recent development on innovation design of reconfigurable mechanisms in China

Wuxiang ZHANG, Shengnan LU, Xilun DING

《机械工程前沿(英文)》 2019年 第14卷 第1期   页码 15-20 doi: 10.1007/s11465-018-0517-7

摘要: Reconfigurable mechanisms can deliberately reconfigure themselves by rearranging the connectivity of components to meet the different requirements of tasks. Metamorphic and origami-derived mechanisms are two kinds of typical reconfigurable mechanisms, which have attracted increasing attention in the field of mechanisms since they were proposed. Improving the independent design level, innovation, and international competitive powers of reconfigurable mechanical products is important. Summarizing related significant innovation research and application achievements periodically will shed light on research directions and promote academic exchanges. This paper presents an overview of recent developments in innovation design of reconfigurable mechanisms in China, including metamorphic and origami mechanisms and their typical applications. The future development trends are analyzed and forecasted.

关键词: innovation design     reconfigurable mechanisms     metamorphic mechanisms     origami-derived mechanisms     development trends    

CROP DIVERSITY AND SUSTAINABLE AGRICULTURE: MECHANISMS, DESIGNS AND APPLICATIONS

《农业科学与工程前沿(英文)》 2021年 第8卷 第3期   页码 359-361 doi: 10.15302/J-FASE -2021417

摘要:

Intensive monoculture agriculture has contributed greatly to global food supply over many decades, but the excessive use of agricultural chemicals (fertilizers, herbicides and pesticides) and intensive cultivation systems has resulted in negative side effects, such as soil erosion, soil degradation, and non-point source pollution[1]. To many observers, agriculture looms as a major global threat to nature conservation and biodiversity. As noted in the Global Biodiversity Outlook 4[2], the drivers associated with food systems and agriculture account for around 70% and 50% of the projected losses by 2050 of terrestrial and freshwater biodiversity, respectively[3].

In addition, agricultural development and modernization of agriculture has led to a decline in the total number of plant species upon which humans depend for food[4]. Currently, fewer than 200 of some 6000 plant species grown for food contribute substantially to global food output, and only nine species account for 67% of total crop production[3]. The global crop diversity has declined in past decades.

Crop species diversity at a national scale was identified as one of the most important factors that stabilize grain production at a national level[5]. A group of long-term field experiments demonstrated that crop diversity also stabilizes temporal grain productivity at field level[6]. Therefore, maintaining crop diversity at both national and field levels is of considerable importance for food security at national and global scales.

Crop diversity includes temporal (crop rotation) and spatial diversity (e.g., intercropping, agroforestry, cultivar mixtures and cover crops) at field scale. Compared to intensive monocultures, diversified cropping systems provide additional options to support multiple ecosystem functions. For instance, crop diversity may increase above- and belowground biodiversity, improve yield stability, reduce pest and disease damage, reduce uses of chemicals, increase the efficiency of the use land, light water and nutrient resources, and enhance stress resilience in agricultural systems.

To highlight advances in research and use of crop diversity, from developing and developed countries, we have prepared this special issue on “Crop Diversity and Sustainable Agriculture” for Frontiers of Agricultural Sciences and Engineering, mainly focusing on intercropping.

Intercropping, growing at least two crops at the same time as a mixture, for example, in alternate rows or strips, is one effective pathway for increasing crop diversity at the field scale. Over recent decades, there have been substantial advances in terms of understanding of processes between intercropped species and applications in practice. There are 10 articles in this special issue including letters, opinions, review and research articles with contributions from Belgium, China, Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Switzerlands, UK, and Mexico etc.

The contributors are internationally-active scientists and agronomists contributing to intercropping research and extension. For example, Antoine Messean is coordinator of the EU H2020 Research project DiverIMPACTS “Diversification through rotation, intercropping, multiple cropping, promoted with actors and value chains towards sustainability”. Eric Justes is coordinator of the EU H2020 Research project ReMIX “Redesigning European cropping systems based on species mixtures”. Maria Finckh has worked on crop cultivar mixture and organic agriculture over many years. Henrik Hauggaard-Nielsen has outstanding expertise in intercropping research and applications, moving from detailed studies on species interactions in intercropping to working with farmers and other stakeholders to make intercropping work in practical farming. In addition to these established scientists, young scientists who have taken an interest in intercropping also contribute to the special issue, including Wen-Feng Cong, Yixiang Liu, Qi Wang, Hao Yang and others.

The first contribution to this special issue addresses how to design cropping systems to reach crop diversification, with Wen-Feng Cong and coworkers ( https://doi.org/10.15302/J-FASE-2021392) considering that it is necessary to optimize existing and/or design novel cropping systems based on farming practices and ecological principles, and to strengthen targeted ecosystem services to achieve identified objectives. In addition, the design should consider regional characteristics with the concurrent objectives of safe, nutritious food production and environmental protection.

The benefits of crop diversification have been demonstrated in many studies. Wen-Feng Cong and coworkers describe the benefits of crop diversification at three scales: field, farm, and landscape. Hao Yang and coauthors reviewed the multiple functions of intercropping. Intercropping enhances crop productivity and its stability, it promotes efficient use of resources and saves mineral fertilizer, controls pests and diseases of crops and reduces the use of pesticides. It mitigates climate change by sequestering carbon in soil, reduces non-point source pollution, and increases above- and belowground biodiversity of other taxa at field scale ( https://doi.org/10.15302/J-FASE-2021398).

Eric Justes and coworkers proposed the “4C” framework to help understand the role of species interactions in intercropping ( https://doi.org/10.15302/J-FASE-2021414). The four components are competition, complementary, cooperation (facilitation) and compensation, which work often simultaneously in intercropping. Hao Yang and coworkers used the concept of diversity effect from ecology to understand the contribution of complementarity and selection effects to enhanced productivity in intercropping. The complementarity effect consists of interspecific facilitation and niche differentiation between crop species, whereas the selection effect is mainly derived from competitive processes between species such that one species dominates the other ( https://doi.org/10.15302/J-FASE-2021398). Also, Luis Garcia-Barrios and Yanus A. Dechnik-Vazquez dissected the ecological concept of the complementarity and selection effects to develop a relative multicrop resistance index to analyze the relation between higher multicrop yield and land use efficiency and the different ecological causes of overyielding under two contrasting water stress regimes ( https://doi.org/10.15302/J-FASE-2021412).

Odette Denise Weedon and Maria Renate Finckh found that composite cross populations, with different disease susceptibilities of three winter wheat cultivars, were moderately resistant to brown rust and even to the newly emerged stripe rust races prevalent in Europe since 2011, but performance varied between standard and organic management contexts ( https://doi.org/10.15302/J-FASE-2021394).

Comparing the performance of intercrops and sole crops is critical to make a sound evaluation of the benefits of intercropping and assess interactions between species choice, intercrop design, intercrop management and factors related to the production situation and pedoclimatic context. Wopke van der Werf and coworkers review some of the metrics that could be used in the quantitative synthesis of literature data on intercropping ( https://doi.org/10.15302/J-FASE-2021413).

Interspecific interactions provide some of the advantages of intercropping, and can be divided into above- and belowground interactions. Aboveground interactions can include light and space competition, which is influenced by crop species traits. Root exudates are also important in interspecific interactions between intercropped or rotated species. Qi Wang and coworkers estimated the light interception of growth stage of maize-peanut intercropping and corresponding monocultures, and found that intercropping has higher light interception than monoculture, and increasing plant density did not further increase light interception of intercropping ( https://doi.org/10.15302/J-FASE-2021403). Yuxin Yang and coworkers reported that the root exudates of fennel (Foeniculum vulgare) can reduce infection of tobacco by Phytophthora nicotianae via inhibiting the motility and germination of the spores of the pathogen ( https://doi.org/10.15302/J-FASE-2021399).

Focusing on the application of intercropping, Wen-Feng Cong and coworkers formulated species recommendations for different regions of China for different crop diversity patterns and crop species combinations. These authors also suggested three steps for implementing crop diversification on the North China Plain. Although there are multiple benefits of crop diversification, its extension and application are hindered by various technical, organizational, and institutional barriers along value chains, especially in Europe. Based on the findings of the European Crop Diversification Cluster projects, Antoine Messéan and coworkers suggested that there needs to be more coordination and cooperation between agrifood system stakeholders, and establish multiactor networks, toward an agroecological transition of European agriculture ( https://doi.org/10.15302/J-FASE-2021406). In addition, Henrik Hauggaard-Nielsen and coworkers report the outcomes of a workshop for participatory research to overcome the barriers to enhanced coordination and networking between stakeholders ( https://doi.org/10.15302/J-FASE-2021416).

Intercropping, though highly effective in labor-intensive agriculture, may be difficult to implement in machine-intensive, large-scale modern agriculture because appropriate large equipment is not commercially available for planting and harvesting various crop mixtures grown with strip intercropping[6]. Thus, the appropriate machinery will need to be developed for further practical application in large-scale agriculture.

As the guest editors, we thank all the authors and reviewers for their great contributions to this special issue on “Crop Diversity and Sustainable Agriculture”. We also thank the FASE editorial team for their kind supports.

Mass transport mechanisms within pervaporation membranes

Yimeng Song, Fusheng Pan, Ying Li, Kaidong Quan, Zhongyi Jiang

《化学科学与工程前沿(英文)》 2019年 第13卷 第3期   页码 458-474 doi: 10.1007/s11705-018-1780-1

摘要: Pervaporation is an energy-efficient membrane technology for separating liquid molecules of similar physical properties, which may compete or combine with distillation separation technology in a number of applications. With the rapid development of new membrane materials, the pervaporation performance was significantly improved. Fundamental understanding of the mass transport mechanisms is crucial for the rational design of membrane materials and efficient intensification of pervaporation process. Based on the interactions between permeate molecules and membranes, this review focuses on two categories of mass transport mechanisms within pervaporation membranes: physical mechanism (solution-diffusion mechanism, molecular sieving mechanism) and chemical mechanism (facilitated transport mechanism). Furthermore, the optimal integration and evolution of different mass transport mechanisms are briefly introduced. Material selection and relevant applications are highlighted under the guidance of mass transport mechanisms. Finally, the current challenges and future perspectives are tentatively identified.

关键词: pervaporation membrane     mass transport mechanisms     physical mechanism     chemical mechanism    

Special issue: Mechanisms and robotics

Jingjun YU

《机械工程前沿(英文)》 2016年 第11卷 第2期   页码 117-118 doi: 10.1007/s11465-016-0399-5

Effects and mechanisms of acupuncture on women related health

《医学前沿(英文)》 doi: 10.1007/s11684-023-1051-5

摘要: Globally, public health interventions have resulted in a 30-year increase in women’s life expectancy. However, women’s health has not increased when socioeconomic status is ignored. Women’s health has become a major public health concern, for those women from developing countries are still struggling with infectious and labor-related diseases, and their counterparts in developed countries are suffering from physical and psychological disorders. In recent years, complementary and alternative medicine has attracted wide attentions with regards to maintaining women’s health. Acupuncture, a crucial component of traditional Chinese medicine, has been used to treat many obstetric and gynecological diseases for thousands of years due to its analgesic and anti-inflammatory effects and its effects on stimulating the sympathetic/parasympathetic nervous system. To fully understand the mechanism through which acupuncture exerts its effects in these diseases would significantly extend the list of available interventions and would allow for more reasonable advice to be given to general practitioners. Therefore, by searching PubMed and CNKI regarding the use of acupuncture in treating obstetric and gynecological diseases, we aimed to summarize the proven evidence of using acupuncture in maintaining women’s health by considering both its effectiveness and the underlying mechanisms behind its effects.

关键词: acupuncture     women health     clinical efficacy     mechanism    

Molecular mechanisms of fatty liver in obesity

null

《医学前沿(英文)》 2015年 第9卷 第3期   页码 275-287 doi: 10.1007/s11684-015-0410-2

摘要:

Nonalcoholic fatty liver disease (NAFLD) covers a spectrum of liver disorders ranging from simple steatosis to advanced pathologies, including nonalcoholic steatohepatitis and cirrhosis. NAFLD significantly contributes to morbidity and mortality in developed societies. Insulin resistance associated with central obesity is the major cause of hepatic steatosis, which is characterized by excessive accumulation of triglyceride-rich lipid droplets in the liver. Accumulating evidence supports that dysregulation of adipose lipolysis and liver de novo lipogenesis (DNL) plays a key role in driving hepatic steatosis. In this work, we reviewed the molecular mechanisms responsible for enhanced adipose lipolysis and increased hepatic DNL that lead to hepatic lipid accumulation in the context of obesity. Delineation of these mechanisms holds promise for developing novel avenues against NAFLD.

关键词: nonalcoholic fatty liver disease     insulin resistance     obesity    

Robust topology optimization of hinge-free compliant mechanisms with material uncertainties based on

Junjie ZHAN, Yangjun LUO

《机械工程前沿(英文)》 2019年 第14卷 第2期   页码 201-212 doi: 10.1007/s11465-019-0529-y

摘要: This paper presents a new robust topology optimization framework for hinge-free compliant mechanisms with spatially varying material uncertainties, which are described using a non-probabilistic bounded field model. Bounded field uncertainties are efficiently represented by a reduced set of uncertain-but-bounded coefficients on the basis of the series expansion method. Robust topology optimization of compliant mechanisms is then defined to minimize the variation in output displacement under constraints of the mean displacement and predefined material volume. The nest optimization problem is solved using a gradient-based optimization algorithm. Numerical examples are presented to illustrate the effectiveness of the proposed method for circumventing hinges in topology optimization of compliant mechanisms.

关键词: compliant mechanisms     robust topology optimization     hinges     uncertainty     bounded field    

INTERACTIONS BETWEEN ABOVE AND BELOW GROUND PLANT STRUCTURES: MECHANISMS AND ECOSYSTEM SERVICES

《农业科学与工程前沿(英文)》 2022年 第9卷 第2期   页码 197-213 doi: 10.15302/J-FASE-2021433

摘要:

Interactions between above and below ground parts of plants can be considered under the (overlapping) categories of energy, material and information. Solar energy powers photosynthesis and transpiration by above ground structures, and drives most water uptake through roots and supplies energy as organic matter to below ground parts, including diazotrophic symbionts and mycorrhizas. Material transfer occurs as water and dissolved soil-derived elements transport up the xylem, and a small fraction of water moving up the xylem with dissolved organic carbon and other solutes down the phloem. The cytosolic nature of sieve tubes accounts for at least some of the cycling of K, Mg and P down the phloem. NO3 assimilation of above ground parts requires organic N transport down phloem with, in some cases, organic anions related to shoot acid-base regulation. Long-distance information transfer is related development, biotic and abiotic damage, and above and below ground resource excess and limitation. Information transfer can involve hydraulic, electrical and chemical signaling, with their varying speeds of transmission and information content. Interaction of above and below ground plant parts is an important component of the ecosystem service of storing atmospheric CO2 as organic C in soil, a process that has decreased since the origin of agriculture.

关键词: aerenchyma / carbon accumulation / hormones / phloem / xylem    

Emergence mechanisms of group consensus in social networks

《工程管理前沿(英文)》 doi: 10.1007/s42524-023-0277-x

摘要: Reaching consensus within larger social network groups has emerged as a pivotal concern in the digital age of connectivity. This article redefines group consensus as the emergence of collective intelligence resulting from self-organizing actions and interactions of individuals within a social network group. In our exploration of extant research on group consensus, we illuminate two frequently underestimated, yet noteworthy facets: Dynamism and emergence. In contrast to the conventional perspective of consensus as a mere outcome, we perceive it as an ongoing, dynamic process. This process encompasses self-organized communication and interaction among group members, collectively guiding the group towards cognitive convergence and viewpoint integration. Consequently, it is imperative to redirect our focus from the outcomes of group interactions to an examination of the relationships and processes underpinning consensus formation, thus elucidating the mechanisms responsible for the generation of group consensus. The amalgamation of cognitive contexts and accurate simplification of real-world scenarios for simulation and experimental analysis offers a pragmatic operational approach. This study contributes novel theoretical underpinnings and quantitative insights for establishing and sustaining group consensus within the realm of engineering management practices. Concurrently, it holds substantial importance for advancing the broader research landscape pertaining to social consensus.

关键词: group consensus     social network     collective intelligence    

标题 作者 时间 类型 操作

The influence of brain death on donor liver and the potential mechanisms of protective intervention

null

期刊论文

Theoretical insights into influence of additives on sulfamethoxazole crystal growth kinetics and mechanisms

期刊论文

Influence of extracellular polymeric substances from activated sludge on the aggregation kinetics of

期刊论文

Catalytic activity of noble metal nanoparticles toward hydrodechlorination: influence of catalyst electronic

Man ZHANG,Feng HE,Dongye ZHAO

期刊论文

FOOD SYSTEMS TRANSFORMATION: CONCEPTS, MECHANISMS AND PRACTICES

期刊论文

Gripping mechanisms in current wood harvesting machines

D. GOUBET, J. C. FAUROUX, G. GOGU

期刊论文

Recent development on innovation design of reconfigurable mechanisms in China

Wuxiang ZHANG, Shengnan LU, Xilun DING

期刊论文

CROP DIVERSITY AND SUSTAINABLE AGRICULTURE: MECHANISMS, DESIGNS AND APPLICATIONS

期刊论文

Mass transport mechanisms within pervaporation membranes

Yimeng Song, Fusheng Pan, Ying Li, Kaidong Quan, Zhongyi Jiang

期刊论文

Special issue: Mechanisms and robotics

Jingjun YU

期刊论文

Effects and mechanisms of acupuncture on women related health

期刊论文

Molecular mechanisms of fatty liver in obesity

null

期刊论文

Robust topology optimization of hinge-free compliant mechanisms with material uncertainties based on

Junjie ZHAN, Yangjun LUO

期刊论文

INTERACTIONS BETWEEN ABOVE AND BELOW GROUND PLANT STRUCTURES: MECHANISMS AND ECOSYSTEM SERVICES

期刊论文

Emergence mechanisms of group consensus in social networks

期刊论文